Article Responses
1) Researchers uncover insights into rare genetic disorders:
http://www.news-medical.net/news/20120530/Researchers-uncover-insights-into-rare-genetic-disorders.aspx
Researchers found a disorder that occurs when cells divide. They found that mutations destroy the cohesion complex which are proteins that surround the chromosomes and cause a series of diseases called cohesinopathies which cause cohesion disorders. The cohesion complex mutation is a reason why Cornelia deLange syndrome occurs, this syndrome has many effects such as heart defects, feeding problems and much more. Researchers found another gene that causes physical harm when it becomes mutated, the gene is known as RAD21. They gathered 101 children and examined them to see if they had the syndrome which
none of them did but one boy had RAD21. Three children were missing the RAD21 gene and in two children those diseases were mutated which caused them to grow short and different facial features. When RAD21 becomes mutated, it stops the cohesion complex to repair the DNA.
I thought that this article was very informative. Researchers discovered a new genetic disorder that has many symptoms, it showed scientists found it and what it does to humans. Finding new and rare disease is especially important because some people may be diagnosed with it. The ideas in the article would impact me as a citizen because someone I know may have these symptoms or I may get it one day and so you should understand why it happens and if you can do anything about it. The discovery will impact me as a student because I gain more knowledge on how genetics plays a role in getting diseases and how mutated genes can be very harmful. The discovery will affect a professional because they have found a new gene mutation and they will be looking forward to finding out more about it. While we have found the disorder, we can’t do anything to solve it because there is no cure for it yet. The next step is to find cures (if possible) for it. Finding new diseases is important but finding cures is even better.
Researchers uncover insights into rare genetic disorders. (n.d.). News Medical. Retrieved May 18, 2012, from
www.news-medical.net/news/20120530/Researchers-uncover-insights-into-rare-genetic-disorders.aspx
2) Migraine Genes Pinpointed By Researchers:
http://www.huffingtonpost.com/2012/06/11/migraine-genes-predispose-without-aura_n_1587327.html
European and Australian researchers discovered four new genes involved in migraines without aura. Two other genes were confirmed to have a role in the presence of this type of migraines. DNA from 2,300 individuals who experienced migraines and
DNA from 4,580 people from the general population were looked at. Migraines are due to genetic and environmental factors. Discovering the genes provided an area of where more genes involved in migraines could be found. Migraines can occur
with or without aura. Migraines that occur without aura have symptoms such as throbbing head pain, nausea, light sensitivity, sound sensitivity and blurry vision. Migraines with an aura include symptoms of problem speaking, and loss vision.
I thought the article was very informative. It demonstrated how although certain conditions have a genetic and environmental basis, uncovering the genetic basis is important. Finding the genes involved, could help with determining appropriate medication to cure migraines. As a citizen, the ideas in this article impact me as someone I know may encounter this condition and so understanding the genetic basis behind this condition it would help determine who in my family could be affected. As a student, the ideas here further my knowledge and provide real world examples of how genetics impacts humans. Here we see how genes provide one reason why we experience certain conditions. Lastly, as a professional in the field, this article impacts me because it provides new research and a new discovery that has been made. As stated by Dr.Stephen Silberstein in the article, this is just the beginning. This is one step forward which can be used to continue to do research and focus into the specific genes involved in migraines. The next step for the ideas in this article would be to do further research into the four newly discovered genes. Since these four are not confirmed to be involved in causing migraines yet, research could be done into these genes. Other genes found close to the confirmed two genes involved in migraines could also be examined to determine if any other genes are involved in migraines.
Migraine Genes Pinpointed By Researchers. (n.d.). Breaking News and Opinion on The Huffington Post. Retrieved June 15, 2012, from http://www.huffingtonpost.com/2012/06/11/migraine-genes-predispose-without-aura_n_1587327.html
http://www.news-medical.net/news/20120530/Researchers-uncover-insights-into-rare-genetic-disorders.aspx
Researchers found a disorder that occurs when cells divide. They found that mutations destroy the cohesion complex which are proteins that surround the chromosomes and cause a series of diseases called cohesinopathies which cause cohesion disorders. The cohesion complex mutation is a reason why Cornelia deLange syndrome occurs, this syndrome has many effects such as heart defects, feeding problems and much more. Researchers found another gene that causes physical harm when it becomes mutated, the gene is known as RAD21. They gathered 101 children and examined them to see if they had the syndrome which
none of them did but one boy had RAD21. Three children were missing the RAD21 gene and in two children those diseases were mutated which caused them to grow short and different facial features. When RAD21 becomes mutated, it stops the cohesion complex to repair the DNA.
I thought that this article was very informative. Researchers discovered a new genetic disorder that has many symptoms, it showed scientists found it and what it does to humans. Finding new and rare disease is especially important because some people may be diagnosed with it. The ideas in the article would impact me as a citizen because someone I know may have these symptoms or I may get it one day and so you should understand why it happens and if you can do anything about it. The discovery will impact me as a student because I gain more knowledge on how genetics plays a role in getting diseases and how mutated genes can be very harmful. The discovery will affect a professional because they have found a new gene mutation and they will be looking forward to finding out more about it. While we have found the disorder, we can’t do anything to solve it because there is no cure for it yet. The next step is to find cures (if possible) for it. Finding new diseases is important but finding cures is even better.
Researchers uncover insights into rare genetic disorders. (n.d.). News Medical. Retrieved May 18, 2012, from
www.news-medical.net/news/20120530/Researchers-uncover-insights-into-rare-genetic-disorders.aspx
2) Migraine Genes Pinpointed By Researchers:
http://www.huffingtonpost.com/2012/06/11/migraine-genes-predispose-without-aura_n_1587327.html
European and Australian researchers discovered four new genes involved in migraines without aura. Two other genes were confirmed to have a role in the presence of this type of migraines. DNA from 2,300 individuals who experienced migraines and
DNA from 4,580 people from the general population were looked at. Migraines are due to genetic and environmental factors. Discovering the genes provided an area of where more genes involved in migraines could be found. Migraines can occur
with or without aura. Migraines that occur without aura have symptoms such as throbbing head pain, nausea, light sensitivity, sound sensitivity and blurry vision. Migraines with an aura include symptoms of problem speaking, and loss vision.
I thought the article was very informative. It demonstrated how although certain conditions have a genetic and environmental basis, uncovering the genetic basis is important. Finding the genes involved, could help with determining appropriate medication to cure migraines. As a citizen, the ideas in this article impact me as someone I know may encounter this condition and so understanding the genetic basis behind this condition it would help determine who in my family could be affected. As a student, the ideas here further my knowledge and provide real world examples of how genetics impacts humans. Here we see how genes provide one reason why we experience certain conditions. Lastly, as a professional in the field, this article impacts me because it provides new research and a new discovery that has been made. As stated by Dr.Stephen Silberstein in the article, this is just the beginning. This is one step forward which can be used to continue to do research and focus into the specific genes involved in migraines. The next step for the ideas in this article would be to do further research into the four newly discovered genes. Since these four are not confirmed to be involved in causing migraines yet, research could be done into these genes. Other genes found close to the confirmed two genes involved in migraines could also be examined to determine if any other genes are involved in migraines.
Migraine Genes Pinpointed By Researchers. (n.d.). Breaking News and Opinion on The Huffington Post. Retrieved June 15, 2012, from http://www.huffingtonpost.com/2012/06/11/migraine-genes-predispose-without-aura_n_1587327.html